15 Chromosome represents more than 3% of the total DNA in cells. People normally have two copies of this chromosome as all other non-sex chromosomes. Chromosome fifteen spans about 100 million base pairs. Base Pairs are two molecules (nucleotides) on opposite DNA strands that are connected. Adenine (A) forms a base pair with thymine (T), as does guanine (G) with cytosine (C) in DNA. Base pairs is how DNA is measured. There are about 945 genes in this chromosome.

This chromosome is related to smoking and lung cancer. Scientists find link between genetic defect on chromosome 15 and epilepsy. A subset of patients with epilepsy lack a certain part of this chromosome.

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