Nuclear DNA, also called
deoxyribonucleic acid. It is DNA contained within a nucleus of all living
things. In most cases it is passed sexually rather than maternally. nDNA is
the most common DNA used in forensic examinations. Of the 23 pairs of
chromosomes in your body, 22 pairs are of nuclear DNA.
nDNA is not an exact replication of the DNA of the
individualís parents, but rather a mixing of their nuclear DNA. As a
result, some individualís chromosomes will be similar to that of the
On the other hand, some of the individualís chromosomes
will have experienced crossing over during meiosis, thereby resulting in mixed
chromosomes. Meiosis is the stage during which two-part cell division occurs
in organisms that reproduce sexually. During this stage, cell division results
in gametes that have half the number of chromosomes of the parent cell.
mitochondrial DNA, which is an exact replica of the DNA of the individualís
mother, nDNA does not provide a genetic profile that establishes a direct
link between an individual and his parents. This makes nDNA a less clear-cut
tool in establishing the biological relationships between the remains found of
different individuals in archaeological excavations. In addition,
more difficult to obtain than mtDNA, because nDNA is found in lower quantities.
mtDNA is preferred to nuclear DNA when conducting DNA
analysis of ancient human remains discovered during archaeological
excavations, because it provides experts with a higher level of accuracy when
creating an individualís DNA profile and when comparing this profile to those
of potential relations.
Autosomal DNA Testing is for your Nuclear DNA.